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Honoring the Past, Advancing the Future
Milestones in breast cancer research mark incredible progress in prevention, detection, and treatment. Each breakthrough brings new hope for earlier diagnoses, better outcomes, and a future where breast cancer is far less threatening.

Edwin Smith Papyrus
Egyptian surgical papyrus (Edwin Smith), M0006276. Wellcome Collection. In copyrightThe oldest known description of breast tumors are found in the Edwin Smith Egyptian papyrus documents

Radical Mastectomy
William Halsted develops the first radical mastectomy, the first standardized surgical treatment

Tamoxifen
Tamoxifen (PubChem CID: 2733526). PubChem, National Center for Biotechnology Information. CC BY 4.0.ICI 46,474 (as it was first known tamoxifen) was synthesized

BRCA1 AND BRCA2
Discovery of BRCA1 and BRCA2 gene mutations, linking inherited risk to breast and ovarian cancers

CDK4/6 Inhibitors
Palbociclib (2D structure), PubChem CID: 5330286. PubChem, NCBI. CC BY 4.0FDA approves the first CDK4/6 inhibitor, Palbociclib, for metastatic hormone-positive breast cancer

Liquid Biopsies
Advances in liquid biopsies (blood tests to detect cancer DNA) and personalized medicine shaping treatment
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